Research: New Salmonella Findings from University of Washington Discussed
Ultrarapid Detection of Pathogenic Bacteria Using a 3D Immunomagnetic Flow Assay.
By a News Reporter-Staff News Editor at Health & Medicine Week -- Data detailed on Proteobacteria have been presented. According to news originating from Seattle, Washington, by NewsRx correspondents, research stated, "We developed a novel 3D immunomagnetic flow assay for the rapid detection of pathogenic bacteria in a large-volume food sample. Antibody-functionalized magnetic nanoparticle clusters (AbMNCs) were magnetically immobilized on the surfaces of a 3D-printed cylindrical microchannel."
Our news journalists obtained a quote from the research from the University of Washington, "The injection of a Salmonella-spiked sample solution into the microchannel produced instant binding between the AbMNCs and the Salmonella bacteria due to their efficient collisions. Nearly perfect capture of the AbMNCs and AbMNCs-Salmonella complexes was achieved under a high flow rate by stacking permanent magnets with spacers inside the cylindrical separator to maximize the magnetic force. The concentration of the bacteria in solution was determined using ATP luminescence measurements. The detection limit was better than 10 cfu/mL, and the overall assay time, including the binding, rinsing, and detection steps for a 10 mL sample took less than 3 min."
According to the news editors, the research concluded: "To our knowledge, the 3D immunomagnetic flow assay described here provides the fastest high-sensitivity, high-capacity method for the detection of pathogenic bacteria."
For more information on this research see: Ultrarapid Detection of Pathogenic Bacteria Using a 3D Immunomagnetic Flow Assay. Analytical Chemistry, 2014;86(13):6683-6688. Analytical Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Analytical Chemistry - www.pubs.acs.org/journal/ancham)
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