Through intensive research, Elanco has succeeded in setting an innovation standard in Salmonella prevention. Live vaccines manufactured in Germany are attenuated under the Metabolic Drift Mutation technology, which reduces the risk of reversion to virulence and enables a reliable differentiation from the field strains (Linde et al, 1997). The easy application via drinking water of the live vaccine parallels the natural path of infection and triggers off multiple immune mechanisms against Salmonella infections: Secretory IgA + Cellular Immunity + Colonization Inhibition effect (Barrow and Methner, 2013).